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Optimizing the dynamics of protein expression

Heterologously expressed genes require adaptation to the host organism to ensure adequate levels of protein synthesis, which is typically approached by replacing codons by the target organism’s preferred codons. In view of frequently encountered suboptimal outcomes we introduce the codon-specific el...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Trösemeier, Jan-Hendrik, Rudorf, Sophia, Loessner, Holger, Hofner, Benjamin, Reuter, Andreas, Schulenborg, Thomas, Koch, Ina, Bekeredjian-Ding, Isabelle, Lipowsky, Reinhard, Kamp, Christel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525252/
https://ncbi.nlm.nih.gov/pubmed/31101858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43857-5
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