Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells

Variants of triggering receptor expressed on myeloid cells 2 (TREM2) are associated with an increased incidence of Alzheimer’s disease, as well as other neurodegenerative disorders. Using a newly developed, highly sensitive reporter cell model, consisting of Jurkat T cells stably overexpressing a re...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Shirotani, Keiro, Hori, Yuma, Yoshizaki, Ryohei, Higuchi, Eri, Colonna, Marco, Saito, Takashi, Hashimoto, Shoko, Saido, Takaomi C., Iwata, Nobuhisa
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525155/
https://ncbi.nlm.nih.gov/pubmed/31101881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43535-6
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