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Pharmacokinetics of fixed-dose combination of atorvastatin and metformin compared with individual tablets

Purpose: The aims of this study was to investigate the mutual pharmacokinetic interactions between steady-state atorvastatin and metformin and the effect of food on the fixed-dose combined (FDC) tablet of atorvastatin and metformin extended release (XR). Subjects and methods: Study 1, an open-labele...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Ghim, Jong-Lyul, Phuong, Nguyen Thi Thu, Kim, Min Jung, Kim, Eun-Ji, Song, Geun Seog, Ahn, Sangzin, Shin, Jae-Gook, Kim, Eun-Young
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6525001/
https://ncbi.nlm.nih.gov/pubmed/31190741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S193254
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