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Effects of Plasmin on von Willebrand Factor and Platelets: A Narrative Review

Plasmin is the major fibrinolytic protease responsible for dissolving thrombi by cleavage of its primary substrate fibrin. In addition, emerging evidence points to other roles of plasmin: (1) as a back-up for ADAMTS13 in proteolysis of ultra-large von Willebrand factor (VWF) multimers and (2) as an...

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Dettagli Bibliografici
Pubblicato in:TH Open
Autori principali: van der Vorm, Lisa N., Remijn, Jasper A., de Laat, Bas, Huskens, Dana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Georg Thieme Verlag KG 2018
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524877/
https://ncbi.nlm.nih.gov/pubmed/31249945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0038-1660505
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