Spectral complexity of 5-ALA induced PpIX fluorescence in guided surgery: a clinical study towards the discrimination of healthy tissue and margin boundaries in high and low grade gliomas

Gliomas are diffuse and hard to cure brain tumors. A major reason for their aggressive behavior is their property to infiltrate the brain. The gross appearance of the infiltrative component is comparable to normal brain, constituting an obstacle to extended surgical resection. 5-ALA induced PpIX flu...

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Publicat a:Biomed Opt Express
Autors principals: Alston, L., Mahieu-Williame, L., Hebert, M., Kantapareddy, P., Meyronet, D., Rousseau, D., Guyotat, J., Montcel, B.
Format: Artigo
Idioma:Inglês
Publicat: Optical Society of America 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524587/
https://ncbi.nlm.nih.gov/pubmed/31149380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.002478
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