Peripheral blood T lymphocytes are downregulated by the PD-1/PD-L1 axis in advanced gastric cancer

INTRODUCTION: Programmed death-1 (PD-1) and programmed death ligand-1 (PD-L1) function as an immune checkpoint pathway that can be exploited by tumor cells to evade immuno-surveillance. The precise role of PD-1/PD-L1 inhibition of the immune response in GC is unknown. The study investigated PD-1 and...

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Vydáno v:Arch Med Sci
Hlavní autoři: Zgodzinski, Witold, Grywalska, Ewelina, Zinkiewicz, Krzysztof, Surdacka, Agata, Majewski, Marek, Zakoscielny, Artur, Bury, Pawel, Rolinski, Jacek, Wallner, Grzegorz T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Termedia Publishing House 2018
Témata:
Basic Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524198/
https://ncbi.nlm.nih.gov/pubmed/31110545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2018.75092
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