In vitro and in vivo evaluations of nanocrystalline Zn-doped carbonated hydroxyapatite/alginate microspheres: zinc and calcium bioavailability and bone regeneration

Background: Zinc-doped hydroxyapatite has been proposed as a graft biomaterial for bone regeneration. However, the effect of zinc on osteoconductivity is still controversial, since the release and resorption of calcium, phosphorus, and zinc in graft-implanted defects have rarely been studied. Method...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Martinez-Zelaya, Victor R, Zarranz, Laila, Herrera, Edher Z, Alves, Adriana T, Uzeda, Marcelo José, Mavropoulos, Elena, Rossi, André L, Mello, Alexandre, Granjeiro, José M, Calasans-Maia, Monica D, Rossi, Alexandre M
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6524140/
https://ncbi.nlm.nih.gov/pubmed/31190805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S197157
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