Transcriptomic Response to 1,25-Dihydroxyvitamin D in Human Fibroblasts with or without a Functional Vitamin D Receptor (VDR): Novel Target Genes and Insights into VDR Basal Transcriptional Activity

The vitamin D receptor (VDR) mediates vitamin D actions beyond bone health. While VDR activation by 1,25-dihydroxyvitamin D (1,25D) leads to robust transcriptional regulation, less is known about VDR actions in the absence of 1,25D. We analyzed the transcriptomic response to 1,25D in fibroblasts bea...

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Veröffentlicht in:Cells
Hauptverfasser: Costa, Pedro L. F., França, Monica M., Katayama, Maria L., Carneiro, Eduardo T., Martin, Regina M., Folgueira, Maria A. K., Latronico, Ana C., Ferraz-de-Souza, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523947/
https://ncbi.nlm.nih.gov/pubmed/30959822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040318
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