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Mutagenesis of DsbAss is Crucial for the Signal Recognition Particle Mechanism in Escherichia coli: Insights from Molecular Dynamics Simulations

The disulfide bond signal sequence (DsbAss) protein is characterized as an important virulence factor in gram-negative bacteria. This study aimed to analyze the “alanine” alteration in the hydrophobic (H) region of DsbAss and to understand the conformational DsbAss alteration(s) inside the fifty-fou...

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Vydáno v:Biomolecules
Hlavní autoři: Durrani, Faiza Gul, Gul, Roquyya, Mirza, Muhammad Usman, Kaderbhai, Naheed Nazly, Froeyen, Matheus, Saleem, Mahjabeen
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523802/
https://ncbi.nlm.nih.gov/pubmed/30987187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9040133
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