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MicroRNAs Mediated Regulation of Expression of Nucleoside Analog Pathway Genes in Acute Myeloid Leukemia

Nucleoside analog, cytarabine (ara-C) is the mainstay of acute myeloid leukemia (AML) chemotherapy. Cytarabine and other nucleoside analogs require activation to the triphosphate form (ara-CTP). Intracellular ara-CTP levels demonstrate significant inter-patient variation and have been related to the...

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Detalhes bibliográficos
Publicado no:Genes (Basel)
Main Authors: Bhise, Neha S., Elsayed, Abdelrahman H., Cao, Xueyuan, Pounds, Stanley, Lamba, Jatinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523677/
https://ncbi.nlm.nih.gov/pubmed/31022985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes10040319
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