Characteristics of Skin Deposition of Itraconazole Solubilized in Cream Formulation

Itraconazole (ITZ) is an anti-fungal agent generally used to treat cutaneous mycoses. For efficient delivery of ITZ to the skin tissues, an oil-in-water (O/W) cream formulation was developed. The O/W cream base was designed based on the solubility measurement of ITZ in various excipients. A physical...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Kim, Hyeongmin, Jung, Sukkyun, Yeo, Sooho, Kim, Dohyun, Na, Young Chae, Yun, Gyiae, Lee, Jaehwi
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523664/
https://ncbi.nlm.nih.gov/pubmed/31013633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11040195
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