Synthesis and Characterization of Covalently Crosslinked pH-Responsive Hyaluronic Acid Nanogels: Effect of Synthesis Parameters

Stable hyaluronic acid nanogels were obtained following the water-in-oil microemulsion method by covalent crosslinking with three biocompatible crosslinking agents: Divinyl sulfone, 1,4-butanediol diglycidyl ether (BDDE), and poly(ethylene glycol) bis(amine). All nanoparticles showed a pH-sensitive...

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Bibliographic Details
Published in:Polymers (Basel)
Main Authors: Maiz-Fernández, Sheila, Pérez-Álvarez, Leyre, Ruiz-Rubio, Leire, Pérez González, Raúl, Sáez-Martínez, Virginia, Ruiz Pérez, Jesica, Vilas-Vilela, José Luis
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523595/
https://ncbi.nlm.nih.gov/pubmed/31022975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym11040742
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