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Inhibition of Oncogenic Kinases: An In Vitro Validated Computational Approach Identified Potential Multi-Target Anticancer Compounds

Tumorigenesis in humans is a multistep progression that imitates genetic changes leading to cell transformation and malignancy. Oncogenic kinases play a central role in cancer progression, rendering them putative targets for the design of anti-cancer drugs. The presented work aims to identify the po...

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Publicat a:Biomolecules
Autors principals: Ikram, Nazia, Mirza, Muhammad Usman, Vanmeert, Michiel, Froeyen, Matheus, Salo-Ahen, Outi M. H., Tahir, Muhammad, Qazi, Aamer, Ahmad, Sarfraz
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523505/
https://ncbi.nlm.nih.gov/pubmed/30925835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9040124
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