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MMP-9 Downregulation with Lipid Nanoparticles for Inhibiting Corneal Neovascularization by Gene Silencing

Gene silencing targeting proangiogenic factors have been shown to be a useful strategy in the treatment of corneal neovascularization (CNV). Among interference RNA (RNAi) molecules, short-hairpin RNA (shRNA) is a plasmid-coded RNA able to down-regulate the expression of the desired gene. It is conti...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Nanomaterials (Basel)
Hauptverfasser: Torrecilla, Josune, Gómez-Aguado, Itziar, Vicente-Pascual, Mónica, del Pozo-Rodríguez, Ana, Solinís, María Ángeles, Rodríguez-Gascón, Alicia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523231/
https://ncbi.nlm.nih.gov/pubmed/31003493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano9040631
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