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Targeting Hedgehog (Hh) Pathway for the Acute Myeloid Leukemia Treatment

The Hedgehog (Hh) pathway, containing the Patched (PTCH) and Smoothened (SMO) multitransmembrane proteins, is the main regulator of vertebrate embryonic development. A non-canonical Hh pathway was recently observed in numerous types of solid cancers and hematological malignancies. Although acute mye...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Terao, Toshiki, Minami, Yosuke
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523210/
https://ncbi.nlm.nih.gov/pubmed/30987263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040312
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