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Targeting Hedgehog (Hh) Pathway for the Acute Myeloid Leukemia Treatment

The Hedgehog (Hh) pathway, containing the Patched (PTCH) and Smoothened (SMO) multitransmembrane proteins, is the main regulator of vertebrate embryonic development. A non-canonical Hh pathway was recently observed in numerous types of solid cancers and hematological malignancies. Although acute mye...

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Publicado en:Cells
Autores principales: Terao, Toshiki, Minami, Yosuke
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6523210/
https://ncbi.nlm.nih.gov/pubmed/30987263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8040312
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