Novel 3-((2-chloroquinolin-3-yl)methylene)indolin-2-one derivatives produce anticancer efficacy in ovarian cancer in vitro

A novel series of 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones were synthesized, using the ‘molecular hybridization approach’ and evaluated for anticancer efficacy. Eleven 3-((2-chloroquinolin-3-yl)methylene)indolin-2-ones (LM01 to LM11) were synthesized and evaluated for in vitro cytotoxic ef...

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Veröffentlicht in:Heliyon
Hauptverfasser: Karthikeyan, Chandrabose, Amawi, Haneen, Ashby, Charles R., Khare, Vishwa M., Jones, Veronica, Hari Narayana Moorthy, N.S., Trivedi, Piyush, Tiwari, Amit K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522656/
https://ncbi.nlm.nih.gov/pubmed/31193218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2019.e01603
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