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Pazopanib in advanced soft tissue sarcomas

Pazopanib is the first and only tyrosine kinase inhibitor currently approved for the treatment of multiple histological subtypes of soft tissue sarcoma (STS). Initially developed as a small molecule inhibitor of vascular endothelial growth factor receptors, preclinical work indicates that pazopanib...

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Pubblicato in:Signal Transduct Target Ther
Autori principali: Lee, Alex T. J., Jones, Robin L., Huang, Paul H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522548/
https://ncbi.nlm.nih.gov/pubmed/31123606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41392-019-0049-6
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