Ciclopirox inhibits Hepatitis B Virus secretion by blocking capsid assembly

Chronic hepatitis B virus (HBV) infection can cause cirrhosis and hepatocellular carcinoma and is therefore a serious public health problem. Infected patients are currently treated with nucleoside/nucleotide analogs and interferon α, but this approach is not curative. Here, we screen 978 FDA-approve...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Kang, Jung-Ah, Kim, Songwon, Park, Minji, Park, Hyun-Jin, Kim, Jeong-Hyun, Park, Sanghyeok, Hwang, Jeong-Ryul, Kim, Yong-Chul, Jun Kim, Yoon, Cho, Yuri, Sun Jin, Mi, Park, Sung-Gyoo
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522524/
https://ncbi.nlm.nih.gov/pubmed/31097716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10200-5
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