Oral versus Intravenous Antibiotics for Bone and Joint Infection

BACKGROUND: The management of complex orthopedic infections usually includes a prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is noninferior to intravenous antibiotic therapy for this indication. METHODS: We enrolled adults who were being treated f...

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Detalhes bibliográficos
Publicado no:N Engl J Med
Main Authors: Li, H.-K., Rombach, I., Zambellas, R., Walker, A.S., McNally, M.A., Atkins, B.L., Lipsky, B.A., Hughes, H.C., Bose, D., Kümin, M., Scarborough, C., Matthews, P.C., Brent, A.J., Lomas, J., Gundle, R., Rogers, M., Taylor, A., Angus, B., Byren, I., Berendt, A.R., Warren, S., Fitzgerald, F.E., Mack, D.J.F., Hopkins, S., Folb, J., Reynolds, H.E., Moore, E., Marshall, J., Jenkins, N., Moran, C.E., Woodhouse, A.F., Stafford, S., Seaton, R.A., Vallance, C., Hemsley, C.J., Bisnauthsing, K., Sandoe, J.A.T., Aggarwal, I., Ellis, S.C., Bunn, D.J., Sutherland, R.K., Barlow, G., Cooper, C., Geue, C., McMeekin, N., Briggs, A.H., Sendi, P., Khatamzas, E., Wangrangsimakul, T., Wong, T.H.N., Barrett, L.K., Alvand, A., Old, C.F., Bostock, J., Paul, J., Cooke, G., Thwaites, G.E., Bejon, P., Scarborough, M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522347/
https://ncbi.nlm.nih.gov/pubmed/30699315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1710926
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