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KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer

Epigenetic regulation of chromatin plays a critical role in controlling stem cell function and tumorigenesis. The histone lysine demethylase, KDM5B, which catalyzes the demethylation of histone 3 lysine 4 (H3K4), is important for embryonic stem (ES) cell differentiation, and is a critical regulator...

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Detalhes bibliográficos
Publicado no:Semin Cancer Biol
Main Authors: Xhabija, Besa, Kidder, Benjamin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522339/
https://ncbi.nlm.nih.gov/pubmed/30448242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2018.11.001
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