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Fast and robust deconvolution of tumor infiltrating lymphocyte from expression profiles using least trimmed squares

Gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently...

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Detalles Bibliográficos
Publicado en:PLoS Comput Biol
Main Authors: Hao, Yuning, Yan, Ming, Heath, Blake R., Lei, Yu L., Xie, Yuying
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6522071/
https://ncbi.nlm.nih.gov/pubmed/31059559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006976
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