Pharmacokinetics and Safety of Icotinib Hydrochloride Cream in Patients with Mild to Moderate Chronic Plaque Psoriasis: A Randomized Double-Blind Vehicle-Controlled Phase 1 Study

OBJECTIVE: This phase I study aimed to systematically assess the safety, local tolerability, pharmacokinetics, and preliminary efficacy of topical icotinib hydrochloride cream in patients with mild to moderate plaque psoriasis. MATERIALS AND METHODS: Eligible Chinese adult patients with mild to mode...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Liu, Lunfei, Lou, Honggang, Zhou, Jiong, Shen, Ying, Zheng, Min, Ruan, Zourong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Clinical Study
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521334/
https://ncbi.nlm.nih.gov/pubmed/31187048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/9072683
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