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Improving Payload Capacity and Anti-Tumor Efficacy of Mesenchymal Stem Cells Using TAT Peptide Functionalized Polymeric Nanoparticles

Mesenchymal stem cells (MSCs) accumulate specifically in both primary tumors and metastases following systemic administration. However, the poor payload capacity of MSCs limits their use in small molecule drug delivery. To improve drug payload in MSCs, we explored polymeric nanoparticles that were f...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Moku, Gopikrishna, Layek, Buddhadev, Trautman, Lana, Putnam, Samuel, Panyam, Jayanth, Prabha, Swayam
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521160/
https://ncbi.nlm.nih.gov/pubmed/30959908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040491
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