Hesperidin Alleviates Methotrexate-Induced Memory Deficits via Hippocampal Neurogenesis in Adult Rats

Methotrexate (MTX), a folic acid antagonist, is widely used in cancer treatment. However, treatment with MTX reduces hippocampal neurogenesis, leading to memory deficits. Hesperidin (Hsd) is a flavonoid glycoside that promotes anti-inflammation, acts as an antioxidant, and has neuroprotective proper...

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Vydáno v:Nutrients
Hlavní autoři: Naewla, Salinee, Sirichoat, Apiwat, Pannangrong, Wanassanan, Chaisawang, Pornthip, Wigmore, Peter, Welbat, Jariya Umka
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521088/
https://ncbi.nlm.nih.gov/pubmed/31027240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu11040936
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