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Cyclin-Dependent Kinase 5 (CDK5)-Mediated Phosphorylation of Upstream Stimulatory Factor 2 (USF2) Contributes to Carcinogenesis

The transcription factor USF2 is supposed to have an important role in tumor development. However, the regulatory mechanisms contributing to the function of USF2 are largely unknown. Cyclin-dependent kinase 5 (CDK5) seems to be of importance since high levels of CDK5 were found in different cancers...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Chi, Tabughang Franklin, Horbach, Tina, Götz, Claudia, Kietzmann, Thomas, Dimova, Elitsa Y.
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6521020/
https://ncbi.nlm.nih.gov/pubmed/31013770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040523
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