Orthotopic Patient-Derived Xenografts of Gastric Cancer to Decipher Drugs Effects on Cancer Stem Cells and Metastatic Dissemination

Gastric cancer is the third leading cause of cancer mortality worldwide. Cancer stem cells (CSC) are at the origin of tumor initiation, chemoresistance, and the formation of metastases. However, there is a lack of mouse models enabling the study of the metastatic process in gastric adenocarcinoma (G...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Giraud, Julie, Bouriez, Damien, Seeneevassen, Lornella, Rousseau, Benoit, Sifré, Elodie, Giese, Alban, Mégraud, Francis, Lehours, Philippe, Dubus, Pierre, Gronnier, Caroline, Varon, Christine
Format: Artigo
Language:Inglês
Published: MDPI 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520896/
https://ncbi.nlm.nih.gov/pubmed/31010193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040560
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