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Total Synthesis of Mycalisine B

The first total synthesis of the marine nucleoside Mycalisine B—a naturally occurring and structurally distinct 4,5-unsaturated 7-deazapurine nucleoside—has been accomplished in 10 linear steps with 27.5% overall yield from commercially available 1,2,3,5-tetra-O-acetyl-ribose and tetracyanoethylene....

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Détails bibliographiques
Publié dans:Mar Drugs
Auteurs principaux: Ding, Haixin, Ruan, Zhizhong, Kou, Peihao, Dong, Xiangyou, Bai, Jiang, Xiao, Qiang
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520845/
https://ncbi.nlm.nih.gov/pubmed/31013980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17040226
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