HNRNPL Restrains miR-155 Targeting of BUB1 to Stabilize Aberrant Karyotypes of Transformed Cells in Chronic Lymphocytic Leukemia

Aneuploidy and overexpression of hsa-miR-155-5p (miR-155) characterize most solid and hematological malignancies. We recently demonstrated that miR-155 sustains aneuploidy at early stages of in vitro cellular transformation. During in vitro transformation of normal human fibroblast, upregulation of...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Pagotto, Sara, Veronese, Angelo, Soranno, Alessandra, Balatti, Veronica, Ramassone, Alice, Guanciali-Franchi, Paolo E., Palka, Giandomenico, Innocenti, Idanna, Autore, Francesco, Rassenti, Laura Z., Kipps, Thomas J., Mariani-Costantini, Renato, Laurenti, Luca, Croce, Carlo M., Visone, Rosa
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520824/
https://ncbi.nlm.nih.gov/pubmed/31018621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040575
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