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Chronic Treatment with Multi-Kinase Inhibitors Causes Differential Toxicities on Skeletal and Cardiac Muscles

Despite recent progress, chemotherapy remains the preferred treatment for cancer. We have shown a link between anticancer drugs and the development of cachexia, i.e., body wasting accompanied by muscle loss. The multi-kinase inhibitors (MKIs) regorafenib and sorafenib, used as second-line treatment...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Huot, Joshua R., Essex, Alyson L., Gutierrez, Maya, Barreto, Rafael, Wang, Meijing, Waning, David L., Plotkin, Lilian I., Bonetto, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520777/
https://ncbi.nlm.nih.gov/pubmed/31018508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11040571
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