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Therapeutic Potential of Multifunctional Tacrine Analogues
Abstract: Tacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease....
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| Publicado no: | Curr Neuropharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6520589/ https://ncbi.nlm.nih.gov/pubmed/29651948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X16666180412091908 |
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