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Generation of a Jurkat-based fluorescent reporter cell line to evaluate lipid antigen interaction with the human iNKT cell receptor

Invariant natural killer T (iNKT) cells are a specialized subset of T cells contributing to both, the innate and adaptive immune responses. In contrast to conventional T lymphocytes they recognize lipid antigens. The aim of the project is to establish a novel model system, to study iNKT-TCR – ligand...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Humeniuk, Piotr, Geiselhart, Sabine, Battin, Claire, Webb, Tonya, Steinberger, Peter, Paster, Wolfgang, Hoffmann-Sommergruber, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520406/
https://ncbi.nlm.nih.gov/pubmed/31092850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43529-4
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