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Possible activation of NRF2 by Vitamin E/Curcumin against altered thyroid hormone induced oxidative stress via NFĸB/AKT/mTOR/KEAP1 signalling in rat heart

Oxidative stress is implicated in both hypo- and hyper-thyroid conditions. In the present study an attempt has been made to elucidate possible interaction between vitamin E or/and curcumin (two established antioxidants) with active portion (redox signaling intervening region) of nuclear factor eryth...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Mishra, Pallavi, Paital, Biswaranjan, Jena, Srikanta, Swain, Shasank S., Kumar, Sunil, Yadav, Manoj K., Chainy, Gagan B. N., Samanta, Luna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520394/
https://ncbi.nlm.nih.gov/pubmed/31092832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43320-5
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