Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer

TP53 mutations are common in colorectal cancer (CRC). Most TP53 sequencing studies have been restricted to coding regions, but recent studies have revealed that splice mutations can generate transcript variants with distinct tumorigenic and prognostic properties. Here, we performed unrestricted sequ...

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Detalhes bibliográficos
Publicado no:Oncogenesis
Main Authors: Smeby, Jørgen, Sveen, Anita, Eilertsen, Ina A., Danielsen, Stine A., Hoff, Andreas M., Eide, Peter W., Johannessen, Bjarne, Hektoen, Merete, Skotheim, Rolf I., Guren, Marianne G., Nesbakken, Arild, Lothe, Ragnhild A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520361/
https://ncbi.nlm.nih.gov/pubmed/31092812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-019-0141-3
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