Recurrent SMARCB1 Inactivation in Epithelioid Malignant Peripheral Nerve Sheath Tumors

Epithelioid malignant peripheral nerve sheath tumors (EMPNST) are characterized by diffuse S-100 and SOX10 positivity, frequent immunohistochemical loss of SMARCB1 expression (70%), and rare association with neurofibromatosis type 1. Some cases arise in a pre-existing epithelioid schwannoma (ESCW),...

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Udgivet i:Am J Surg Pathol
Main Authors: Schaefer, Inga-Marie, Dong, Fei, Garcia, Elizabeth P., Fletcher, Christopher D. M., Jo, Vickie Y.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6520153/
https://ncbi.nlm.nih.gov/pubmed/30864974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000001242
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