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Mitochondrial protection partly mitigates kidney cellular senescence in swine atherosclerotic renal artery stenosis

BACKGROUND/AIMS: Atherosclerotic renal artery stenosis (ARAS) may cause kidney injury and mitochondrial dysfunction, which is linked to cellular senescence. Elamipretide, a mitochondria-targeted peptide, improves renal function in ARAS, but whether it alleviates senescence is unknown. We hypothesize...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Physiol Biochem
Main Authors: Kim, Seo Rin, Erin, Alfonso, Zhang, Xin, Lerman, Amir, Lerman, Lilach O.
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519989/
https://ncbi.nlm.nih.gov/pubmed/30907989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33594/000000044
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