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Evaluation of a sequential enzyme immunoassay testing algorithm for Lyme disease demonstrates lack of test independence but high diagnostic specificity

To diagnose Lyme disease, a two-tier testing algorithm is used in which supplemental IgM and IgG immunoblots to detect antibody to Borrelia burgdorferi are reflexively performed if a first-tier assay, such as a whole-cell sonicate-based enzyme immunoassay (WCS EIA), is reactive. Recent data suggest...

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Detalhes bibliográficos
Publicado no:Diagn Microbiol Infect Dis
Main Authors: Wormser, Gary P., Molins, Claudia R., Levin, Andrew, Lipsett, Susan C., Nigrovic, Lise E., Schriefer, Martin E., Branda, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519922/
https://ncbi.nlm.nih.gov/pubmed/29550060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.diagmicrobio.2018.02.006
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