HLA alleles, especially amino-acid signatures of HLA-DPB1, might contribute to the molecular pathogenesis of early-onset autoimmune thyroid disease

The major histocompatibility complex region has been suggested to play an important role in the development of autoimmune thyroid disease (AITD). In this study, we investigated the associations of human leukocyte antigen (HLA) alleles and amino acid variants of HLA with early-onset AITD. HLA class I...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Shin, Dong-Hwan, Baek, In-Cheol, Kim, Hyung Jae, Choi, Eun-Jeong, Ahn, Moonbae, Jung, Min Ho, Suh, Byung-Kyu, Cho, Won Kyoung, Kim, Tai-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519818/
https://ncbi.nlm.nih.gov/pubmed/31091281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0216941
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