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Genetic variation in metronidazole metabolism and oxidative stress pathways in clinical Giardia lamblia assemblage A and B isolates

Purpose: Treatment-refractory Giardia cases have increased rapidly within the last decade. No markers of resistance nor a standardized susceptibility test have been established yet, but several enzymes and their pathways have been associated with metronidazole (MTZ) resistant Giardia. Very limited d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Infect Drug Resist
Hauptverfasser: Saghaug, Christina S, Klotz, Christian, Kallio, Juha P, Brattbakk, Hans-Richard, Stokowy, Tomasz, Aebischer, Toni, Kursula, Inari, Langeland, Nina, Hanevik, Kurt
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519707/
https://ncbi.nlm.nih.gov/pubmed/31190910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S177997
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