Lugdunomycin, an Angucycline‐Derived Molecule with Unprecedented Chemical Architecture

The angucyclines form the largest family of polycyclic aromatic polyketides, and have been studied extensively. Herein, we report the discovery of lugdunomycin, an angucycline‐derived polyketide, produced by Streptomyces species QL37. Lugdunomycin has unique structural characteristics, including a h...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wu, Changsheng, van der Heul, Helga U., Melnik, Alexey V., Lübben, Jens, Dorrestein, Pieter C., Minnaard, Adriaan J., Choi, Young Hae, van Wezel, Gilles P.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6519343/
https://ncbi.nlm.nih.gov/pubmed/30656821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201814581
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