Replacing cyclophosphamide/cytarabine/mercaptopurine with cyclophosphamide/etoposide during consolidation/delayed intensification does not improve outcome for pediatric B-cell acute lymphoblastic leukemia: a report from the COG

With modern chemotherapy, approximately 90% of patients with pediatric acute lymphoblastic leukemia are now cured. However, subsets of patients can be identified who remain at very high risk of relapse with expected 4-year disease-free survival rates <80%; such patients are appropriate candidates...

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Udgivet i:Haematologica
Main Authors: Burke, Michael J., Salzer, Wanda L., Devidas, Meenakshi, Dai, Yunfeng, Gore, Lia, Hilden, Joanne M., Larsen, Eric, Rabin, Karen R., Zweidler-McKay, Patrick A., Borowitz, Michael J., Wood, Brent, Heerema, Nyla A., Carroll, Andrew J., Winick, Naomi, Carroll, William L., Raetz, Elizabeth A., Loh, Mignon L., Hunger, Stephen P.
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518909/
https://ncbi.nlm.nih.gov/pubmed/30545921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.204545
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