Ischemia time impacts on respiratory chain functions and Ca(2+)-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury

BACKGROUND: Mitochondrial impairment can result from myocardial ischemia reperfusion injury (IR). Despite cardioplegic arrest, IR-associated cardiodepression is a major problem in heart surgery. We determined the effect of increasing ischemia time on the respiratory chain (RC) function, the inner me...

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Detalhes bibliográficos
Publicado no:J Cardiothorac Surg
Main Authors: Leistner, Marcus, Sommer, Stefanie, Kanofsky, Peer, Leyh, Rainer, Sommer, Sebastian-Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518521/
https://ncbi.nlm.nih.gov/pubmed/31088484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13019-019-0911-1
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