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Unique and redundant β-catenin regulatory roles of two Dishevelled paralogs during C. elegans asymmetric cell division

The Wnt/β-catenin signaling pathway is utilized across metazoans. However, the mechanism of signal transduction, especially dissociation of the β-catenin destruction complex by Dishevelled proteins, remains controversial. Here, we describe the function of the Dishevelled paralogs DSH-2 and MIG-5 in...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Baldwin, Austin T., Clemons, Amy M., Phillips, Bryan T.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518166/
https://ncbi.nlm.nih.gov/pubmed/26795562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.175802
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