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A rim-and-spoke hypothesis to explain the biomechanical roles for cytoplasmic intermediate filament networks

Textbook images of keratin intermediate filament (IF) networks in epithelial cells and the functional compromization of the epidermis by keratin mutations promulgate a mechanical role for this important cytoskeletal component. In stratified epithelia, keratin filaments form prominent radial spokes t...

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Detalles Bibliográficos
Publicado en:J Cell Sci
Main Authors: Quinlan, Roy A., Schwarz, Nicole, Windoffer, Reinhard, Richardson, Christine, Hawkins, Tim, Broussard, Joshua A., Green, Kathleen J., Leube, Rudolf E.
Formato: Artigo
Idioma:Inglês
Publicado: The Company of Biologists Ltd 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518161/
https://ncbi.nlm.nih.gov/pubmed/29032358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.202168
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