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PCSK9 inhibition: the dawn of a new age in cholesterol lowering?
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a circulating enzyme of hepatic origin that plays a key role in LDL receptor turnover. Genetic studies have confirmed that individuals with gain-of-function PCSK9 mutations have increased PCSK9 activity, elevated LDL-cholesterol levels and a s...
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| Publicado no: | Diabetologia |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6518084/ https://ncbi.nlm.nih.gov/pubmed/28025677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4178-y |
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