Co‐degradation of interferon signaling factor DDX3 by PB1‐F2 as a basis for high virulence of 1918 pandemic influenza

The multifunctional influenza virus protein PB1‐F2 plays several roles in deregulation of host innate immune responses and is a known immunopathology enhancer of the 1918 influenza pandemic. Here, we show that the 1918 PB1‐F2 protein not only interferes with the mitochondria‐dependent pathway of typ...

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Bibliografske podrobnosti
izdano v:EMBO J
Main Authors: Park, Eun‐Sook, Byun, Young Ho, Park, Soree, Jang, Yo Han, Han, Woo‐Ry, Won, Juhee, Cho, Kyung Cho, Kim, Doo Hyun, Lee, Ah Ram, Shin, Gu‐Choul, Park, Yong Kwang, Kang, Hong Seok, Sim, Heewoo, Ha, Yea Na, Jae, Byeongjune, Son, Ahyun, Kim, Paul, Yu, Jieun, Lee, Hye‐Min, Kwon, Sun‐Bin, Kim, Kwang Pyo, Lee, Seung‐Hyun, Park, Yeong‐Min, Seong, Baik L, Kim, Kyun‐Hwan
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6518015/
https://ncbi.nlm.nih.gov/pubmed/30979777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899475
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