UNR/CSDE1 Expression Is Critical to Maintain Invasive Phenotype of Colorectal Cancer through Regulation of c-MYC and Epithelial-to-Mesenchymal Transition

CSDE1 (cold shock domain containing E1) gene is located upstream of the N-RAS locus, and codes for an RNA-binding protein named Upstream of N-Ras (UNR). In cancer, CSDE1 has been shown to regulate c-Fos, c-Myc, Pten, Rac1, or Vimentin. UNR/CSDE1 has been studied in breast, melanoma, pancreatic and p...

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Detalhes bibliográficos
Publicado no:J Clin Med
Main Authors: Martinez-Useros, Javier, Garcia-Carbonero, Nuria, Li, Weiyao, Fernandez-Aceñero, Maria J., Cristobal, Ion, Rincon, Raul, Rodriguez-Remirez, Maria, Borrero-Palacios, Aurea, Garcia-Foncillas, Jesus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517883/
https://ncbi.nlm.nih.gov/pubmed/31027221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm8040560
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