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A Grhl2-dependent gene network controls trophoblast branching morphogenesis

Healthy placental development is essential for reproductive success; failure of the feto-maternal interface results in pre-eclampsia and intrauterine growth retardation. We found that grainyhead-like 2 (GRHL2), a CP2-type transcription factor, is highly expressed in chorionic trophoblast cells, incl...

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Bibliographic Details
Published in:Development
Main Authors: Walentin, Katharina, Hinze, Christian, Werth, Max, Haase, Nadine, Varma, Saaket, Morell, Robert, Aue, Annekatrin, Pötschke, Elisabeth, Warburton, David, Qiu, Andong, Barasch, Jonathan, Purfürst, Bettina, Dieterich, Christoph, Popova, Elena, Bader, Michael, Dechend, Ralf, Staff, Anne Cathrine, Yurtdas, Zeliha Yesim, Kilic, Ergin, Schmidt-Ott, Kai M.
Format: Artigo
Language:Inglês
Published: The Company of Biologists 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517833/
https://ncbi.nlm.nih.gov/pubmed/25758223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.113829
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