Acalabrutinib monotherapy in patients with chronic lymphocytic leukemia who are intolerant to ibrutinib

The Bruton tyrosine kinase (BTK) inhibitor ibrutinib improves patient outcomes in chronic lymphocytic leukemia (CLL); however, some patients experience adverse events (AEs) leading to discontinuation. Acalabrutinib is a potent, covalent BTK inhibitor with greater selectivity than ibrutinib. We evalu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Blood Adv
Prif Awduron: Awan, Farrukh T., Schuh, Anna, Brown, Jennifer R., Furman, Richard R., Pagel, John M., Hillmen, Peter, Stephens, Deborah M., Woyach, Jennifer, Bibikova, Elena, Charuworn, Prista, Frigault, Melanie M., Hamdy, Ahmed, Izumi, Raquel, Linghu, Bolan, Patel, Priti, Wang, Min Hui, Byrd, John C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society of Hematology 2019
Pynciau:
Clinical Trials and Observations
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517672/
https://ncbi.nlm.nih.gov/pubmed/31088809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018030007
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