Alpha-Herpesvirus Thymidine Kinase Genes Mediate Viral Virulence and Are Potential Therapeutic Targets

Alpha-herpesvirus thymidine kinase (TK) genes are virulence-related genes and are nonessential for viral replication; they are often preferred target genes for the construction of gene-deleted attenuated vaccines and genetically engineered vectors for inserting and expressing foreign genes. The enzy...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Xie, Ying, Wu, Liping, Wang, Mingshu, Cheng, Anchun, Yang, Qiao, Wu, Ying, Jia, Renyong, Zhu, Dekang, Zhao, XinXin, Chen, Shun, Liu, Mafeng, Zhang, Shaqiu, Wang, Yin, Xu, Zhiwen, Chen, Zhengli, Zhu, Ling, Luo, Qihui, Liu, Yunya, Yu, Yanling, Zhang, Ling, Chen, Xiaoyue
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517553/
https://ncbi.nlm.nih.gov/pubmed/31134006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00941
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