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MicroRNA-126 regulates Hypoxia-Inducible Factor-1α which inhibited migration, proliferation, and angiogenesis in replicative endothelial senescence

Whereas a healthy endothelium maintains physiological vascular functions, endothelial damage contributes to the development of cardiovascular diseases. Endothelial senescence is the main determinant of endothelial dysfunction and thus of age-related cardiovascular disease. The objective of this stud...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Alique, Matilde, Bodega, Guillermo, Giannarelli, Chiara, Carracedo, Julia, Ramírez, Rafael
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6517399/
https://ncbi.nlm.nih.gov/pubmed/31089163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43689-3
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